Chromatin accessibility landscape of articular knee cartilage reveals aberrant enhancer regulation in osteoarthritis
Ye Liu, Jen-Chien Chang, Chung-Chau Hon, Naoshi Fukui, Nobuho Tanaka, Zhenya Zhang, Ming Ta Michael Lee, Aki Minoda
The paper uses ATAC-seq to analyze chromatin accessibility in knee cartilage from OA patients, identifying enhancer regions linked to OA and potential therapeutic targets.
Scientific Reports · Oct 15, 2018Peer-reviewedGenomics