Control of 3' Splice Site Selection in S. cerevisiae by a Highly Conserved Amino Acid within the Prp8 α-finger Domain
Ye Liu, Joshua C. Paulson, Aaron A. Hoskins
This study shows that a specific amino acid in the Prp8 protein influences 3' splice site selection in yeast by interacting with the -3 pyrimidine of the 3SS, affecting splicing efficiency and 3SS competition.