Msp1-dependent extraction promotes ubiquitylation of translocation-stalled mitochondrial precursor proteins
Jeannine Engelke, Noemi Occhipinti, Lisanne Pitzke, Kira Ritzenhofen, Robert Hardt, Marc Sylvester, Enzo Scifo, Fabian den Brave, Thomas Becker
This study shows that Msp1 and Ubx2 work together to remove stalled mitochondrial precursor proteins by facilitating ubiquitylation and proteasomal degradation.
bioRxiv · Sep 29, 2026 · PreprintMolecular Biology