Fabian den Brave

This study shows that Msp1 and Ubx2 work together to remove stalled mitochondrial precursor proteins by facilitating ubiquitylation and proteasomal degradation.

The paper shows that Vms1 protects mitochondrial import and homeostasis during translation stress by interacting with Msp1.

The paper identifies a quality control mechanism that removes faulty mitochondrial β-barrel proteins through cooperation between mitochondrial and cytosolic factors.

This study identifies Apj1 and Ydj1 as J-domain proteins that regulate Hsf1 in distinct phases of the heat shock response in yeast.

The paper shows that DNA damage triggers rDNA repeat relocation by phosphorylating the CLIP-cohibin complex, leading to SUMOylation and Cdc48/p97-mediated release from the nucleolus in yeast and human cells.