Molecular BiologybioRxivPreprint
The bromodomain inhibitor JQ1 is a molecular glue targeting centromeres
Samuel Corless, Noor Pratap-Singh, Nezha S. Benabdallah…·Sylvia Erhardt
The paper identifies JQ1 as a molecular glue that targets centromeres by stabilizing BRD4-CENP-B interactions, enhancing centromere cohesion and affecting cell proliferation.
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