SAM68-regulated ALE selection of Pcdh15 maintains proper synapse development and function
Mohamed Darwish, Masatoshi Ito, Akinori Takase, Noriko Ayukawa, Satoko Suzuki, Masami Tanaka, Yoko Iijima, Takatoshi Iijima
This study investigates how SAM68 regulates alternative last exon (ALE) splicing of Pcdh15, showing its role in synapse development and function through protein localization and synapse formation.
bioRxiv · Apr 4, 2023 · PreprintNeuroscience