Author

Mohamed Darwish

Tokai UniversityORCID 0009-0004-4301-6675Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Akinori Takase· 2 shared Masami TanakaiD· 2 shared Satoko SuzukiiD· 2 shared Takatoshi IijimaiD· 2 shared Yoko Iijima· 2 shared Akiko Hayashi‐TakagiiD· 1 shared Akinobu MatsumotoiD· 1 shared Akio KiharaiD· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Akinori Takase

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 29, 2023

Activity-regulated micro-exon splicing programs underlie late-onset plasticity at the axon initial segment

Mohamed Darwish, Satoko Suzuki, Yuki Ogawa…·Takatoshi Iijima

The paper identifies micro-exon splicing changes in AIS proteins as a mechanism for activity-regulated late-onset plasticity in cerebellar granule cells.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceeLifePeer-reviewedSep 1, 2023

Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment

Hideo Hagihara, Hirotaka Shoji, Satoko Hattori…·Michihiro Igarashi

The paper investigates brain pH and lactate levels in animal models of neuropsychiatric disorders, finding decreased pH and increased lactate levels as common features across multiple models.

18 citations

mousestatistical model

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 4, 2023

SAM68-regulated ALE selection of Pcdh15 maintains proper synapse development and function

Mohamed Darwish, Masatoshi Ito, Akinori Takase…·Takatoshi Iijima

This study investigates how SAM68 regulates alternative last exon (ALE) splicing of Pcdh15, showing its role in synapse development and function through protein localization and synapse formation.

DOI 10.1101/2023.04.04.535307

mousemultiome

𝕏 PostBluesky