Human Papilloma Virus does not fully inactivate p53 cellular activity in HNSCC
Jovanka Gencel‐Augusto, Hua Li, Liam C. Woerner, Nuo Tian, Ashir A. Borah, Jeffrey N. Myers, Patrick K. Ha, Daniel E. Johnson, Jennifer Rubin Grandis
This study shows that p53 activity persists in HPV+ HNSCC tumors with WT TP53, leading to better survival and therapeutic vulnerabilities.
Head & Neck · Oct 30, 2025Peer-reviewedCancer Biology