Ambroxol Hydrochloride Inhibits the Interaction between Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein's Receptor Binding Domain and Recombinant Human ACE2.
O. A. Olaleye, M. Kaur, C. C. Onyenaka
This study identifies Ambroxol hydrochloride and Bromhexine hydrochloride as inhibitors of the SARS-CoV-2 spike protein RBD interaction with human ACE2, suggesting their potential for repurposing as antiviral drugs.
bioRxiv · Sep 13, 2020 · PreprintPharmacology & Toxicology