The Mammalian Cytosolic Thioredoxin Reductase Pathway Acts via a Membrane Protein to Reduce ER-localised Proteins
X. Cao, S. Lilla, Z. Cao, M. A. Pringle, O. B. Oka, P. J. Robinson, T. Szmaja, M. van Lith, S. Zanivan, N. Bulleid
The paper demonstrates that the cytosolic thioredoxin reductase pathway reduces ER-localized proteins via a membrane protein, essential for ER redox homeostasis and protein folding.
Journal of Cell Science · Apr 30, 2020Peer-reviewedCell Biology