Author

O. E. Torres Montaguth

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Biochemistry· 1

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Approach:microscopy & imaging analysis· 1

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L. Lee· 1 shared M. M. Naqvi· 1 shared M. Szczelkun· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperBiochemistry

L. Lee

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJun 18, 2021

A gate and clamp regulate sequential DNA strand cleavage by CRISPR-Cas12a

M. M. Naqvi, L. Lee, O. E. Torres Montaguth, M. Szczelkun

This study investigates how CRISPR-Cas12a cleaves DNA strands sequentially by observing structural changes and using mutagenesis to show the role of a gate and clamp in the process.

DOI 10.1101/2021.06.18.448962

microscopy & imaging analysis

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