Author

O. Keskin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Gursoy· 1 shared A. GÜRSOY· 1 shared H. Jang· 1 shared K. Kosoglu· 1 shared M. E. Omur· 1 shared M. GÖNEN· 1 shared N. A. LACK· 1 shared R. Nussinov· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperBiophysics

A. Gursoy

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2 papers

Recent·Most cited

The structural basis of the oncogenic mutant K-Ras4B homodimers

K. Kosoglu, M. E. Omur, H. Jang, R. Nussinov, O. Keskin, A. Gursoy

This study uses molecular dynamics simulations to analyze the stability and conformational changes of K-Ras4BG12D homodimers and their mutants, focusing on two dimerization interfaces.

bioRxiv · Sep 7, 2020 · PreprintBiophysics

Androgen receptor binding sites are highly mutated in prostate cancer

T. MOROVA, M. GÖNEN, A. GÜRSOY, O. KESKIN, N. A. LACK

The paper shows that AR binding sites in prostate cancer have high mutation rates, suggesting they may be driver mutations.

Oncology Abstracts · Sep 26, 2019Peer-reviewedCancer Biology