RNA binding is essential for NONO condensates to modulate pre-mRNA processing in neuroblastoma
S. Zhang, J. A. Cooper, Y. S. Chong, A. Naveed, C. Mayoh, N. Jayatillek, T. Liu, S. Amos, S. Kobelke, A. C. Marshall, O. Meers, Y. S. Choi, C. S. Bond, A. H. Fox
This study identifies NONO's role in neuroblastoma by showing its RNA binding is essential for forming condensates that regulate pre-mRNA processing and oncogenic gene expression.
bioRxiv · Feb 28, 2022 · PreprintCell Biology