Author

O. N. Raguimova

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Biophysics· 1

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Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:simulation· 1 Approach:statistical model· 1 Assay:structural biology· 1

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L. M. Espinoza-Fonseca· 1 shared R. Aguayo-Ortiz· 1 shared S. L. Robia· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperBiophysics

L. M. Espinoza-Fonseca

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BiophysicsbioRxivPreprintApr 26, 2020

Dynamics-driven allostery underlies pre-activation of the regulatory Ca2+-ATPase/phospholamban complex

O. N. Raguimova, R. Aguayo-Ortiz, S. L. Robia, L. M. Espinoza-Fonseca

This study uses simulations and experiments to show Ca2+ binding induces structural changes in the SERCA-PLB complex, pre-activating SERCA through dynamic allostery.

DOI 10.1101/2020.04.26.062299

humanstructural biology

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