Erythroid precursors and progenitors suppress adaptive immunity and get invaded by SARS-CoV-2
S. Shahbaz, L. Xu, M. Osman, W. Sligl, J. Shields, M. Joyce, L. Tyrrell, O. Oyegbami, S. Elahi
The paper shows that CD45+CD71+ erythroid cells in COVID-19 patients express SARS-CoV-2 entry factors and are immunosuppressive, suggesting their involvement in hypoxia and erythropoiesis disruption.
bioRxiv · Aug 18, 2020Immunology