Comparison of efficiency and specificity of CRISPR-associated (Cas) nucleases in plants: An expanded toolkit for precision genome engineering
O. Raitskin, C. Schudoma, A. West, N. J. Patron
This study compares the efficiency and specificity of CRISPR-associated nucleases in plants, finding that Staphylococcus aureus Cas9 is most efficient and high-fidelity variants reduce off-target mutations.
bioRxiv · Nov 7, 2018Plant Biology