C. Schudoma

Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations

This study shows that fecal microbial load, not disease, is the main driver of gut microbiome changes and identifies it as a major confounder in microbiome studies.

Large-scale computational analyses of gut microbial CAZyme repertoires enabled by Cayman

The paper develops Cayman, a CAZyme profiler, to analyze gut microbial CAZyme repertoires and finds differences in substrate preferences between Western and non-Western metagenomes and CRC patients.

Machine learning-based meta-analysis reveals gut microbiome alterations associated with Parkinson's disease

This study uses machine learning to meta-analyze gut microbiome data from Parkinson's disease patients, identifying microbial pathways linked to disease and potential diagnostic applications.

C. difficile may be overdiagnosed in adults and is a prevalent commensal in infants

This study finds that C. difficile is often overdiagnosed in adults and is a common commensal in infants, with distinct microbial associations across age groups.

An accessible, efficient and global approach for the large-scale sequencing of bacterial genomes

The paper describes a low-cost, efficient pipeline for large-scale bacterial genome sequencing, demonstrating its application in collecting and sequencing 10,419 isolates from multiple countries.

Conserved secreted effectors determine endophytic growth and multi-host plant compatibility in a vascular wilt fungus

This study identifies conserved fungal effectors that enable multi-host plant colonization and compatibility in the vascular wilt fungus Fusarium oxysporum.

An improved assembly of the Albugo candida Ac2V genome reveals the expansion of the "CCG" class of effectors

The paper improves the genome assembly of Albugo candida Ac2V and identifies a 250% expansion in the CCG effector class.

Convergent gene loss in aquatic plants predicts new components of plant immunity and drought response

The paper identifies convergent gene loss in aquatic plants and links some lost genes to plant immunity and drought response.

Comparison of efficiency and specificity of CRISPR-associated (Cas) nucleases in plants: An expanded toolkit for precision genome engineering

This study compares the efficiency and specificity of CRISPR-associated nucleases in plants, finding that Staphylococcus aureus Cas9 is most efficient and high-fidelity variants reduce off-target mutations.

Dominant integration locus drives continuous diversification of plant immune receptors with exogenous domain fusions