The mechanism of SARS-CoV-2 nucleocapsid protein recognition by the human 14-3-3 proteins
K. V. Tugaeva, D. E. D. P. Hawkins, J. L. R. Smith, O. W. Bayfield, D.-S. Ker, A. A. Sysoev, O. I. Klychnikov, A. A. Antson, N. N. Sluchanko
This paper identifies the molecular mechanism by which phosphorylated SARS-CoV-2 nucleocapsid protein binds to human 14-3-3 proteins, showing that Ser197 phosphorylation is critical for this interaction.
bioRxiv · Dec 26, 2020Biochemistry