Inert and seed-competent tau monomers suggest structural origins of aggregation
Hilda Mirbaha, Dailu Chen, Olga A Morazova, Kiersten M. Ruff, Apurwa M Sharma, Xiaohua Liu, Mohammad Goodarzi, Rohit V. Pappu, David W. Colby, Hamid Mirzaei, Łukasz A. Joachimiak, Marc I. Diamond
The paper identifies inert and seed-competent tau monomers, showing structural differences that influence aggregation potential.
eLife · Jul 9, 2018Peer-reviewedNeuroscience