Astrocytic lysosome deficits reduce alpha-synuclein degradation and induce spread of pathology
Lindsay M. Roth, Olga Morozova, Jan Stöhr, Jason Schapansky
This study shows that astrocytic lysosome deficits impair alpha-synuclein degradation and promote its pathological spread in Parkinson's Disease.
Neurobiology of Disease · Jan 18, 2026Peer-reviewedNeuroscience