Adaptation of the Romanomermis culicivorax CCA-adding enzyme to miniaturized armless tRNA substrates
Oliver Hennig, Susanne Philipp, Sonja Bonin, K. Rollet, Tim Kolberg, Tina Jühling, Heike Betat, Claude Sauter, Mario Mörl
The paper identifies a beta-turn element in the Romanomermis culicivorax tRNA nucleotidyltransferase that enables full CCA-adding activity on armless tRNAs when transplanted into the human enzyme.
International Journal of Molecular Sciences · Nov 28, 2020Peer-reviewedMolecular Biology