Cell cycle-driven transcriptome maturation confers multilineage competence to cardiopharyngeal progenitors
Yelena Y. Bernadskaya, Ariel Kuan, Andreas Tjärnberg, Jonas Brandenburg, Ping Zhang, Keira Wiechecki, Nicole Kaplan, Margaux Failla, Maria Bikou, Oliver Madilian, Noah Bruderer, Wei Wang, Lionel Christiaen
The paper shows that transcriptome maturation during the cell cycle enables multilineage competence in cardiopharyngeal progenitors by coupling fate decisions with cell cycle phases.
The EMBO Journal · Nov 3, 2025Peer-reviewedDevelopmental Biology