Toxoplasma strikes preemptively to swiftly suppress macrophage immune response during active infection
Dominykas Murza, Filip Lastovka, George Wood, Matthew P. Brember, Ollie Chan, James W. Ajioka, Betty Chung
This study uses time-resolved transcriptomic profiling to analyze host and parasite gene expression during early Toxoplasma gondii infection in mouse macrophages, revealing rapid host immune responses and delayed parasite transcriptional activation.
bioRxiv · Jan 31, 2025 · PreprintMicrobiology