One lysine, two acyl marks: 2-hydroxyisobutyrylation and acetylation of G6PD differ in outcome and regulation
Santhosh Paramasivam, Omer Even Hen, Itamar Kass, Fang Wu, Eyal Arbely
This study investigates the site-specific effects of 2-hydroxyisobutyrylation and acetylation on G6PD activity and shows their distinct regulatory roles and deacylase recognition.
bioRxiv · Oct 30, 2026 · PreprintBiochemistry