Author

Santhosh Paramasivam

Ben-Gurion University of the Negev

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Eyal ArbelyiD· 2 shared Fang Wu· 2 shared Albert BatushanskyiD· 1 shared Alejandro Villagra· 1 shared Amit MitraiD· 1 shared Cyril BařinkaiD· 1 shared Itamar KassiD· 1 shared Kavita KundaliD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

Eyal ArbelyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

One lysine, two acyl marks: 2-hydroxyisobutyrylation and acetylation of G6PD differ in outcome and regulation

Santhosh Paramasivam, Omer Even Hen, Itamar Kass, Fang Wu, Eyal Arbely

This study investigates the site-specific effects of 2-hydroxyisobutyrylation and acetylation on G6PD activity and shows their distinct regulatory roles and deacylase recognition.

bioRxiv · Oct 30, 2026 · PreprintBiochemistry

HDAC6 and SSAT2 orchestrate acetyllysine metabolism and protein homeostasis

Fang Wu, Santhosh Paramasivam, Satish Kumar Reddy Noonepalle, Albert Batushansky, Miroslava Vošahlíková, Alejandro Villagra, Cyril Bařinka, Eyal Arbely

The paper identifies HDAC6 and SSAT2 as enzymes regulating acetyllysine metabolism and protein homeostasis through opposing deacetylation and acetylation reactions.

bioRxiv · May 26, 2026 · PreprintBiochemistry

In silico identification of novel peptides as potential modulators of Aβ42 Amyloidogenesis

Kavita Kundal, Santhosh Paramasivam, Amit Mitra, Nandini Sarkar

The paper identifies two peptides, YRIGY and DKAPFF, that modulate Aβ42 amyloidogenesis by either disaggregating fibrils or stabilizing monomers, suggesting potential therapeutic applications for Alzheimer's Disease.

bioRxiv · Apr 20, 2022 · PreprintBioinformatics