Molecular BiologybioRxivPreprint
Modelling APOL1-mediated kidney inflammation and fibrosis using a partially reprogrammed urine derived SIX2-positive renal progenitor cell line.
Chantelle Thimm, Rosanne Mack, Osmond Adjei-Aruna…·James Adjaye
This paper rejuvenates a renal progenitor cell line to model APOL1-mediated kidney inflammation and fibrosis, showing Baricitinib can mitigate IFN-gamma-induced effects.
DOI 10.1101/2025.07.28.667124