Isogenic hiPSC models of Turner syndrome development reveal shared roles of inactive X and Y in the human cranial neural crest network
Darcy T. Ahern, Prakhar Bansal, Isaac V. Faustino, Owen M. Chambers, Erin C. Banda, Heather R. Glatt-Deeley, Rachael E. Massey, Yuvabharath Kondaveeti, Stefan F. Pinter
The paper uses isogenic hiPSC-derived neural crest cells to identify gene expression changes in Turner syndrome, revealing haploinsufficient drivers in cranial neural crest development.
The American Journal of Human Genetics · Feb 7, 2025Peer-reviewedDevelopmental Biology