Erin C. Banda

Chromosome engineering to correct a complex rearrangement on Chromosome 8 reveals the effects of 8p syndrome on gene expression and neural differentiation

This study corrects a complex Chromosome 8 rearrangement in vitro, identifies differentially expressed genes, and shows partial rescue of neural differentiation defects.

Isogenic hiPSC models of Turner syndrome development reveal shared roles of inactive X and Y in the human cranial neural crest network

The paper uses isogenic hiPSC-derived neural crest cells to identify gene expression changes in Turner syndrome, revealing haploinsufficient drivers in cranial neural crest development.

A dynamic in vitro model of Down Syndrome neurogenesis with Trisomy 21 gene dosage correction

This study uses a dynamic in vitro model to correct Trisomy 21 gene dosage in DS neurogenesis and shows XIST can suppress chr21 genes even after terminal differentiation.

Monosomy X in isogenic human iPSC-derived trophoblast model impacts expression modules preserved in human placenta

The paper uses isogenic hiPSCs to study monosomy X effects on trophoblast gene expression and finds altered placental gene levels and preserved co-expression modules in placental tissues.