Author

Owen Smith

University of Victoria

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Genetics· 1

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Adelaide H. Chow· 1 shared Bridget C. Ryan· 1 shared Caitlin N Geczi· 1 shared Kaitlin E. Griffith· 1 shared Katerina E. Kurz· 1 shared Oliver Orchiston· 1 shared Robert L. ChowiD· 1 shared Xiaoya Xie· 1 shared

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2025-2025 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperGenetics

Adelaide H. Chow

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1 paper

Recent·Most cited

Loss of Complement Factor D suppresses alternative pathway activation but fails to reduce lipofuscin accumulation in the retinal pigmented epithelium of Abca4-/- mice

Bridget C. Ryan, Kaitlin E. Griffith, Caitlin N Geczi, Katerina E. Kurz, Oliver Orchiston, Owen Smith, Xiaoya Xie, Adelaide H. Chow, Robert L. Chow

The paper investigates the role of the alternative complement pathway in Stargardt disease by analyzing Abca4-/- and Cfd-/- mice, finding that while the pathway drives complement activation, it does not reduce lipofuscin accumulation.

bioRxiv · Oct 25, 2025 · PreprintGenetics