Multi-scale computational study of the mechanical regulation of cell mitotic rounding in epithelia
A. Nematbakhsh, W. Sun, P. A. Brodskiy, A. Amiri, C. Narciso, Z. Xu, J. J. Zartman, M. S. Alber
This study develops a multi-scale computational model to investigate how mechanical factors regulate mitotic rounding in epithelial tissues, finding that all three factors—adhesion, cortical stiffness, and pressure—must be coordinated for robust rounding.
bioRxiv · Jan 25, 2016Biophysics