Author

P. A. Dalby

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 1

Frequent Co-Authors

A. Cazares-Korner· 1 shared D. Mendez-Sanchez· 1 shared D. Steadman· 1 shared H. C. Hailes· 1 shared H. Yu· 1 shared J. M. Ward· 1 shared L. R. Rios Solis· 1 shared P. Morris· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

A. Cazares-Korner

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2 papers

Recent·Most cited

Biophysical characterization of the inactivation of E. coli transketolase by aqueous co-solvents

P. Morris, R. Garcia Arrazola, L. R. Rios Solis, P. A. Dalby

This paper investigates how polar organic co-solvents affect E. coli transketolase activity and structure, finding that solvent-induced local unfolding, not aggregation, is the main cause of enzyme inactivation.

bioRxiv · Jun 9, 2020 · PreprintBiophysics

Simultaneous optimization of donor and acceptor substrate specificity for transketolase by a small but smart library

H. Yu, R. I. H. Lopez, D. Steadman, D. Mendez-Sanchez, S. Higson, A. Cazares-Korner, J. M. Ward, H. C. Hailes, P. A. Dalby

This paper engineers transketolase to accept novel donor and acceptor substrates, improving catalytic efficiency and stereoselectivity for industrial applications.

bioRxiv · Aug 9, 2019 · PreprintBioengineering