Author

P. A. Romero

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. R. Christopher· 2 shared L. B. Hyman· 2 shared P. Heinzelman· 2 shared H. Roychowdhury· 1 shared J. Greenhalgh· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

5 top collaborators · 2 mutual co-author links

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2 shared papersBioengineering

C. R. Christopher

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Author profile →

5 papers

Recent·Most cited

Directed evolution of angiotensin-converting enzyme 2 (ACE2) peptidase activity profiles for therapeutic applications

P. Heinzelman, P. A. Romero

This paper engineers ACE2 variants with enhanced hydrolytic activity and specificity toward Angiotensin-II, improving therapeutic potential for diseases like ARDS and Alzheimer's.

bioRxiv · Jan 3, 2022Biochemistry

Microfluidic deep mutational scanning of the human executioner caspases reveals differences in structure and regulation

H. Roychowdhury, P. A. Romero

The paper uses microfluidic deep mutational scanning to analyze CASP3 and CASP7 variants, revealing structural and functional differences, including a unique cleavage site in CASP7.

bioRxiv · Jun 8, 2021Biochemistry

Competitive SNP-LAMP probes for rapid and robust single-nucleotide polymorphism detection

L. B. Hyman, C. R. Christopher, P. A. Romero

This paper develops a SNP detection method called competitive SNP-LAMP that enables rapid, specific, and sensitive SNP detection in various contexts.

bioRxiv · Mar 29, 2021Bioengineering

Identification of ACE2 mutations that modulate SARS-CoV-2 spike binding across multiple mammalian species

P. Heinzelman, J. Greenhalgh, P. A. Romero

The paper identifies ACE2 mutations that enhance SARS-CoV-2 spike binding across multiple mammalian species through yeast display-based directed evolution.

bioRxiv · Mar 16, 2021Biochemistry

Single-cell nucleic acid profiling in droplets (SNAPD) enables high-throughput analysis of heterogeneous cell populations

L. B. Hyman, C. R. Christopher, P. A. Romero

SNAPD enables high-throughput analysis of heterogeneous cell populations by profiling transcriptional states of over 100,000 cells per hour.

bioRxiv · Aug 21, 2020Bioengineering