Phenotypic deconvolution in heterogeneous cancer cell populations using drug screening data
A. Köhn-Luque, E. M. Myklebust, D. S. Tadele, M. Giliberto, L. Schmiester, J. Noory, E. Harivel, P. Arsenteva, S. M. Mumenthaler, F. Schjesvold, K. Tasken, J. M. Enserink, K. Leder, A. Frigessi, J. Foo
This paper introduces PhenoPop, a method to deconvolve tumor heterogeneity using drug screening data, identifying subpopulations with differential drug responses and their frequencies.
bioRxiv · Jan 17, 2022Cancer Biology