Author

S. M. Mumenthaler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:deconvolution· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Frigessi· 1 shared A. Köhn-Luque· 1 shared A. Schatz· 1 shared A. Y. Yoon· 1 shared B. Haliday· 1 shared C. Cherry· 1 shared C. Shah· 1 shared C. Strelez· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Frigessi

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2 papers

Recent·Most cited

Integration of Patient-Derived Organoids and Organ-on-Chip Systems: Investigating Colorectal Cancer Invasion within the Mechanical and GABAergic Tumor Microenvironment

C. Strelez, R. Perez, J. S. Chlystek, C. Cherry, A. Y. Yoon, B. Haliday, C. Shah, K. Ghaffarian, R. X. Sun, H. Jiang, R. Lau, A. Schatz, H.-J. Lenz, J. E. Katz, S. M. Mumenthaler

This paper combines patient-derived organoids with a microfluidic organ-on-chip system to study colorectal cancer invasion under mechanical and GABAergic influences, showing enhanced invasiveness in KRAS mutant tumors.

bioRxiv · Sep 14, 2023 · PreprintCancer Biology

Phenotypic deconvolution in heterogeneous cancer cell populations using drug screening data

A. Köhn-Luque, E. M. Myklebust, D. S. Tadele, M. Giliberto, L. Schmiester, J. Noory, E. Harivel, P. Arsenteva, S. M. Mumenthaler, F. Schjesvold, K. Tasken, J. M. Enserink, K. Leder, A. Frigessi, J. Foo

This paper introduces PhenoPop, a method to deconvolve tumor heterogeneity using drug screening data, identifying subpopulations with differential drug responses and their frequencies.

bioRxiv · Jan 17, 2022Cancer Biology