Author

K. Leder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:deconvolution· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

J. Foo· 2 shared A. Frigessi· 1 shared A. K. Li· 1 shared A. Köhn-Luque· 1 shared A. Lin· 1 shared A. Tela· 1 shared C. Greening· 1 shared C. Schang· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

J. Foo

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Author profile →

3 papers

Recent·Most cited

Early ctDNA kinetics as a dynamic biomarker of cancer treatment response

A. K. Li, E. Lou, K. Leder, J. Foo

This study develops a framework to design ctDNA biomarkers for cancer treatment response by modeling ctDNA kinetics and simulating virtual patient cohorts.

bioRxiv · Jul 1, 2024Cancer Biology

Phenotypic deconvolution in heterogeneous cancer cell populations using drug screening data

A. Köhn-Luque, E. M. Myklebust, D. S. Tadele, M. Giliberto, L. Schmiester, J. Noory, E. Harivel, P. Arsenteva, S. M. Mumenthaler, F. Schjesvold, K. Tasken, J. M. Enserink, K. Leder, A. Frigessi, J. Foo

This paper introduces PhenoPop, a method to deconvolve tumor heterogeneity using drug screening data, identifying subpopulations with differential drug responses and their frequencies.

bioRxiv · Jan 17, 2022Cancer Biology

TaqMan Array Cards enable monitoring of diverse enteric pathogens across environmental and host reservoirs

R. Lappan, R. Henry, S. L. Chown, S. P. Luby, E. Higginson, L. Bata, T. Jirapanjawat, C. Schang, J. J. Openshaw, J. O'Toole, A. Lin, A. Tela, T. H. F. Wong, M. A. French, R. R. Brown, , D. McCarthy

This study compares TaqMan Array Cards and standard qPCR for detecting enteric pathogens in diverse samples, finding comparable performance with TAC offering a broader panel at lower cost.

bioRxiv · Oct 27, 2020 · PreprintMicrobiology