Receptor activity modifying protein modulation of parathyroid hormone-1 receptor function and signalling.
P. Avgoustou, A. B. Jailani, A. J. Desai, D. J. Roberts, G. W. Stothard, E. R. Lilley, T. M. Skerry, G. O. Richards
This study investigates how RAMP2 and RAMP3 modulate PTH1R function and signaling, showing RAMP2 enhances responses while RAMP3 reduces them, suggesting potential for targeted therapies.
bioRxiv · Apr 16, 2024 · PreprintPharmacology & Toxicology