A supernumerary synthetic chromosome in Komagataella phaffii as a repository for extraneous genetic material
D. Abramczyk, M. d. C. Sanchez-Olmos, A. A. Ramirez Rojas, D. Schindler, D. Robertson, S. McColm, A. Marston, P. Barlow
This paper describes a stable linear artificial chromosome in Komagataella phaffii that can carry multiple genes for biomanufacturing without disrupting the native genome.
bioRxiv · Oct 5, 2023 · PreprintBioengineering