Author

P. C. Bevilacqua

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

C. D. Keating· 3 shared S. Choi· 3 shared M. O. Meyer· 2 shared A. M. Williams· 1 shared C. X. Chan· 1 shared D. C. Tack· 1 shared E. A. Jolley· 1 shared E. Jolley· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersBiochemistry

C. D. Keating

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

In vivo structure probing of RNA in Archaea: Novel insights into the ribosome structure of Methanosarcina acetivorans

A. M. Williams, E. Jolley, M. G. Santiago-Martinez, C. X. Chan, R. Gutell, J. G. Ferry, P. C. Bevilacqua

This study applies Structure-seq2 to probe in vivo RNA structure in Methanosarcina acetivorans, revealing similarities and differences in rRNA reactivity between methanol and acetate growth conditions.

bioRxiv · Apr 14, 2023Biochemistry

RNA folding studies inside peptide-rich droplets reveal roles of modified nucleosides at the origin of life

M. O. Meyer, R. Yamagami, S. Choi, C. D. Keating, P. C. Bevilacqua

The paper shows that RNA folds into native structures in protocell models, and this is enhanced by covalent modifications, suggesting a role in early life processes.

bioRxiv · Feb 27, 2023Biochemistry

Phase-specific RNA accumulation and duplex thermodynamics in multiphase coacervate models for membraneless organelles

S. Choi, P. C. Bevilacqua, C. D. Keating

This study investigates RNA behavior in multiphase coacervate models, showing phase-specific RNA interactions and duplex stability changes without requiring specific RNA binding sites or full-length proteins.

bioRxiv · May 15, 2021Biochemistry

Prebiotically-relevant low polyion multivalency can improve functionality of membraneless compartments

F. Pir Cakmak, S. Choi, M. O. Meyer, P. C. Bevilacqua, C. D. Keating

This study shows that low multivalency polyions form effective membraneless compartments that enhance RNA function and create distinct microenvironments.

Nature Communications · Nov 23, 2020Peer-reviewedBiophysics

Structure-seq2 probing of RNA structure upon amino acid starvation reveals both known and novel RNA switches in Bacillus subtilis

L. E. Ritchey, D. C. Tack, H. Yakhnin, E. A. Jolley, S. M. Assmann, P. C. Bevilacqua, P. Babitzke

This study uses Structure-seq2 to analyze RNA structure changes in Bacillus subtilis under amino acid starvation, revealing known and novel RNA switches involved in amino acid metabolism.

bioRxiv · Apr 20, 2020Microbiology