Dynamic Allostery Highlights the Evolutionary Differences between the CoV-1 and CoV-2 Main Proteases
P. Campitelli, J. Lu, S. B. Ozkan
This paper compares the dynamic properties of SARS-CoV-1 and SARS-CoV-2 main proteases, finding that CoV-2 exhibits enhanced cross-chain coupling and dynamic allostery due to mutations.
bioRxiv · Oct 2, 2021Biophysics