NK cells integrate signals over large areas when building immune synapses but require local stimuli for degranulation
Q. Verron, E. Forslund, L. Brandt, M. Leino, T. W. Frisk, P. E. Olofsson, B. Önfelt
This study shows that NK cells form immune synapses influenced by ligand spatial distribution, with degranulation requiring local signaling.
bioRxiv · Jul 29, 2020Immunology