Evolutionary adaptation from hydrolytic to oxygenolytic catalysis
S. Bui, S. Gil-Guerrero, P. van der Linden, P. Carpentier, M. Ceccarelli, P. G. Jambrina, R. A. Steiner
This paper investigates how the ABH-fold protein evolved to catalyze oxygenation reactions by repurposing its original hydrolytic function through structural and computational analysis.
bioRxiv · May 5, 2023 · PreprintBiochemistry