Author

P. G. Nelson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Evolutionary Biology· 4

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:yeast· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

J. Masel· 2 shared C. Weibel· 1 shared G. May· 1 shared J. E. James· 1 shared J. G. Masel· 1 shared K. M. Meer· 1 shared K. Xiong· 1 shared L. J. Kosinski· 1 shared

Activity by Year

2017-2020 · peak 1/yr

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9 top collaborators · 13 mutual co-author links

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2 shared papersEvolutionary Biology

J. Masel

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4 papers

Recent·Most cited

Universal and taxon-specific trends in protein sequences as a function of age

J. E. James, S. M. Willis, P. G. Nelson, C. Weibel, L. J. Kosinski, J. Masel

The paper analyzes protein sequence trends across species age, finding universal hydrophobic clustering reduction but taxon-specific structural disorder patterns in young domains.

bioRxiv · Mar 26, 2020Evolutionary Biology

High transcriptional error rates vary as a function of gene expression level

K. M. Meer, P. G. Nelson, K. Xiong, J. Masel

The paper examines transcriptional error rates in E. coli and S. cerevisiae, finding a relationship between gene expression levels and error rates for non-CU errors in E. coli but not in S. cerevisiae.

bioRxiv · Oct 26, 2019Evolutionary Biology

Defensive symbiosis and the evolution of virulence

P. G. Nelson, G. May

The paper models the evolution of defense and virulence in symbionts, finding that increased defense can reduce virulence and enable pathogens to evolve to mutualism, though results depend on the cost of defensive traits.

bioRxiv · Sep 21, 2018Evolutionary Biology

Evolutionary capacitance emerges spontaneously during adaptation to environmental changes

P. G. Nelson, J. G. Masel

The paper shows environmental change can increase evolvability through a byproduct mechanism called emergent evolutionary capacitance, which involves increased molecular errors and purging of deleterious sequences.

bioRxiv · Jan 17, 2017Evolutionary Biology