Identifying Sialylation Linkages at the Glycopeptide Level by Glycosyltransferase Labeling Assisted Mass Spectrometry (GLAMS)
H. Zhu, S. Wang, D. Liu, L. Ding, C. Chen, Y. Liu, Z. Wu, R. Bollag, K. Liu, J. Yin, C. Ma, L. Li, P. G. Wang
The paper introduces GLAMS, a method using glycosyltransferase labeling and mass spectrometry to identify sialylation linkages at the glycopeptide level, successfully identifying 1,236 linkage-specific sialoglycopeptides from human serum.
bioRxiv · Nov 6, 2019Biochemistry