Author

P. Handford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

B. Korona· 1 shared C. Chillakuri· 1 shared D. Koscinski· 1 shared L. Holt· 1 shared P. L. Tubaro· 1 shared P. Li· 1 shared P. Whiteman· 1 shared R. Suckling· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

B. Korona

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2 papers

Recent·Most cited

Phylogeography of two Andean frogs: Test of vicariance versus elevational gradient models of diversification

D. Koscinski, P. Handford, P. L. Tubaro, P. Li, S. C. Lougheed

This study compares two Andean frog species to test vicariance versus elevational gradient models of diversification, finding support for vicariance but differing divergence times between species.

bioRxiv · Oct 25, 2019 · PreprintEvolutionary Biology

Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands

R. Suckling, B. Korona, P. Whiteman, C. Chillakuri, L. Holt, P. Handford, S. Lea

The paper presents structures of Notch ligands and functional assays showing that membrane recognition via the C2 domain is critical for Notch signaling, with mutations affecting this process leading to disease.

bioRxiv · Jan 18, 2017Biochemistry