Ligand-Displaying E. coli Cells and Minicells for Programmable Delivery of Toxic Payloads via Type IV Secretion Systems
P. J. Christie, Y. G. Li, K. Kishida, N. Ogawa-Kishida
This study demonstrates the use of ligand-displaying E. coli cells and minicells to deliver toxic payloads via T4SSs, enhancing conjugative transfer and killing specific bacterial targets.
bioRxiv · Aug 11, 2023 · PreprintMicrobiology