Interleukin-21 Drives a Hypermetabolic State and CD4+ T Cell-associated Pathogenicity in Chronic Intestinal Inflammation
A. O. Bamidele, S. K. Mishra, P. Hirsova, P. J. Fehrenbach, L. Valenzuela-Perez, H. S. Kim Lee
This study shows IL-21 promotes a hypermetabolic state in Tregs, enhancing their inflammatory response in chronic intestinal inflammation.
bioRxiv · Jun 2, 2023Immunology