Author

P. J. Lukavsky

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Biochemistry· 1

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:multiome· 1 Assay:proteomics· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

C. Beaumont· 1 shared C. Stuani· 1 shared E. Buratti· 1 shared M.-Y. Chou· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

C. Beaumont

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1 paper

Recent·Most cited

hnRNP A1 induces aberrant CFTR exon 9 splicing via a newly discovered Exonic Splicing Silencer element.

C. Beaumont, M.-Y. Chou, C. Stuani, E. Buratti, P. J. Lukavsky

This study identifies an exonic splicing silencer element in CFTR exon 9 that is bound by hnRNP A1, leading to exon skipping and non-functional CFTR protein.

bioRxiv · Aug 24, 2023 · PreprintBiochemistry