Optogenetic low-frequency stimulation of dentate granule cells prevents seizure generation in experimental epilepsy
E. Paschen, C. Elgueta, K. Heining, D. M. Vieira, C. Orcinha, U. Häussler, M. Bartos, U. Egert, P. Janz, C. A. Haas
This study shows that optogenetic low-frequency stimulation of entorhinal afferents suppresses seizures in epileptic mice, even with severe hippocampal sclerosis.
bioRxiv · Jan 9, 2020Physiology