P. Katikaridis

The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase

This study identifies ClpL from Listeria monocytogenes as a potent AAA+ disaggregase that enhances heat resistance by efficiently solubilizing protein aggregates under severe stress.

Structural basis of aggregate binding by the AAA+ disaggregase ClpG

The paper determines the structure of the ClpG disaggregase's N1 domain, revealing how it recognizes and binds protein aggregates through hydrophobic interactions and Zn2+ coordination.