Refining Spatial Proteomics by Mass Spectrometry: An Efficient Workflow Tailored for Archival Tissue
R. Daucke, C. V. Rift, N. S. Bager, K. Saxena, P. R. Koffeldt, J. Woessmann, V. Petrosius, E. S. Rugiu, B. W. Kristensen, P. Klausen, E. M. Schoof
This paper develops an efficient workflow for spatial proteomics on FFPE tissue using low-input material, showing that EpCAM staining improves protein identification compared to H&E staining.
BMC Methods · Apr 22, 2026Peer-reviewedBioengineering